VIRUS-RESISTANCE GENES: THE MOUSE MODEL.

  • Pedro Faísca Universidade Lusófona de Humanidades e Tecnologias

Resumo

Human and animals differ widely in their responses to virus infections. Viruses may induce barely discernible symptoms in some of them and severe, life-threatening illness in others. Evidence is accumulating that genetic background is one of the major factors involved, thus, identifying genes that control the response to virus infection is a crucial step in elucidating how they might affect the pathophysiological processes underlying the severity of the disease induced.  In this review, it’s illustrated how mouse-virus systems are being used to identify candidate virus-resistance genes, and how they provide the probes to detect functional homologues of resistance genes that are shared by rodent and other species.

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Biografia Autor

Pedro Faísca, Universidade Lusófona de Humanidades e Tecnologias
Faculdade de Medicina Veterinária-ULHT
Publicado
2010-01-21
Edição
Secção
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